Model validation of simple-graph representations of metabolism

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Model validation of simple-graph representations of metabolism.

The large-scale properties of chemical reaction systems, such as metabolism, can be studied with graph-based methods. To do this, one needs to reduce the information, lists of chemical reactions, available in databases. Even for the simplest type of graph representation, this reduction can be done in several ways. We investigate different simple network representations by testing how well they ...

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ژورنال

عنوان ژورنال: Journal of The Royal Society Interface

سال: 2009

ISSN: 1742-5689,1742-5662

DOI: 10.1098/rsif.2008.0489